Exploiting Adaptive Laboratory Evolution of Streptomyces clavuligerus for Antibiotic Discovery and Overproduction

Adaptation is normally viewed as the enemy of the antibiotic discovery and development process because adaptation among pathogens to antibiotic exposure leads to resistance. We present a method here that, in contrast, exploits the power of adaptation among antibiotic producers to accelerate the disc...

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Detalles Bibliográficos
Autores principales: Charusanti, Pep, Fong, Nicole L., Nagarajan, Harish, Pereira, Alban R., Li, Howard J., Abate, Elisa A., Su, Yongxuan, Gerwick, William H., Palsson, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312335/
https://www.ncbi.nlm.nih.gov/pubmed/22470465
http://dx.doi.org/10.1371/journal.pone.0033727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312335/
https://www.ncbi.nlm.nih.gov/pubmed/22470465
http://dx.doi.org/10.1371/journal.pone.0033727

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