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Effect of αB-Crystallin on Protein Aggregation in Drosophila

Disorganisation and aggregation of proteins containing expanded polyglutamine (polyQ) repeats, or ectopic expression of α-synuclein, underlie neurodegenerative diseases including Alzheimer's, Parkinson, Huntington, Creutzfeldt diseases. Small heat-shock proteins, such as αB-crystallin, act as c...

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Detalles Bibliográficos
Autores principales: Tue, Nguyen Trong, Shimaji, Kouhei, Tanaka, Naoki, Yamaguchi, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312385/
https://www.ncbi.nlm.nih.gov/pubmed/22505806
http://dx.doi.org/10.1155/2012/252049