Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin

The approval of histone deacetylase inhibitors for treatment of lymphoma subtypes has positioned histone modifications as potential targets for the development of new classes of anticancer drugs. Histones also undergo phosphorylation events, and Haspin is a protein kinase the only known target of wh...

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Detalles Bibliográficos
Autores principales: Huertas, D, Soler, M, Moreto, J, Villanueva, A, Martinez, A, Vidal, A, Charlton, M, Moffat, D, Patel, S, McDermott, J, Owen, J, Brotherton, D, Krige, D, Cuthill, S, Esteller, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312407/
https://www.ncbi.nlm.nih.gov/pubmed/21804608
http://dx.doi.org/10.1038/onc.2011.335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312407/
https://www.ncbi.nlm.nih.gov/pubmed/21804608
http://dx.doi.org/10.1038/onc.2011.335

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