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Clinical decision support of therapeutic drug monitoring of phenytoin: measured versus adjusted phenytoin plasma concentrations

BACKGROUND: Therapeutic drug monitoring of phenytoin by measurement of plasma concentrations is often employed to optimize clinical efficacy while avoiding adverse effects. This is most commonly accomplished by measurement of total phenytoin plasma concentrations. However, total phenytoin levels can...

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Detalles Bibliográficos
Autores principales: Krasowski, Matthew D, Penrod, Louis E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312854/
https://www.ncbi.nlm.nih.gov/pubmed/22333264
http://dx.doi.org/10.1186/1472-6947-12-7