FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma

The oncogene FOXM1 has been implicated in all major types of human cancer. We recently showed that aberrant FOXM1 expression causes stem cell compartment expansion resulting in the initiation of hyperplasia. We have previously shown that FOXM1 regulates HELLS, a SNF2/helicase involved in DNA methyla...

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Detalles Bibliográficos
Autores principales: Teh, Muy-Teck, Gemenetzidis, Emilios, Patel, Deeviyaben, Tariq, Rameez, Nadir, Ayesha, Bahta, Adiam W., Waseem, Ahmad, Hutchison, Iain L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312909/
https://www.ncbi.nlm.nih.gov/pubmed/22461910
http://dx.doi.org/10.1371/journal.pone.0034329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312909/
https://www.ncbi.nlm.nih.gov/pubmed/22461910
http://dx.doi.org/10.1371/journal.pone.0034329

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