JWA Deficiency Suppresses Dimethylbenz[a]Anthracene-Phorbol Ester Induced Skin Papillomas via Inactivation of MAPK Pathway in Mice

Our previous studies indicated that JWA plays an important role in DNA damage repair, cell migration, and regulation of MAPKs. In this study, we investigated the role of JWA in chemical carcinogenesis using conditional JWA knockout (JWA (Δ2/Δ2)) mice and two-stage model of skin carcinogenesis. Our r...

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Detalles Bibliográficos
Autores principales: Gong, Zhenghua, Shi, Yaowei, Zhu, Ze, Li, Xuan, Ye, Yang, Zhang, Jianbing, Li, Aiping, Li, Gang, Zhou, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312911/
https://www.ncbi.nlm.nih.gov/pubmed/22461904
http://dx.doi.org/10.1371/journal.pone.0034154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312911/
https://www.ncbi.nlm.nih.gov/pubmed/22461904
http://dx.doi.org/10.1371/journal.pone.0034154

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