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Role of a conserved aspartic acid in nucleotide binding domain 1 (NBD1) of Hsp100 chaperones in their activities

Besides its beneficial role in thermotolerance, the chaperone protein Hsp104 is involved in the inheritance of yeast Saccharomyces cerevisiae prions. Guanidine hydrochloride was previously shown to interfere with Hsp104 chaperone activity in vivo, thus impairing thermotolerance and resulting in prio...

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Detalles Bibliográficos
Autores principales: Nowicki, Łukasz, Leźnicki, Paweł, Morawiec, Ewa, Litwińczuk, Natalia, Liberek, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3312961/
https://www.ncbi.nlm.nih.gov/pubmed/22144132
http://dx.doi.org/10.1007/s12192-011-0312-4