S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice

PURPOSE: To study the protective effects and underlying molecular mechanisms of SAMC on carbon tetrachloride (CCl(4))-induced acute hepatotoxicity in the mouse model. METHODS: Mice were intraperitoneally injected with CCl(4) (50 μl/kg; single dose) to induce acute hepatotoxicity with or without a 2-...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Jia, Liong, Emily C., Ling, Ming-Tat, Ching, Yick-Pang, Fung, Man-Lung, Tipoe, George L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313023/
https://www.ncbi.nlm.nih.gov/pubmed/21681437
http://dx.doi.org/10.1007/s00394-011-0217-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313023/
https://www.ncbi.nlm.nih.gov/pubmed/21681437
http://dx.doi.org/10.1007/s00394-011-0217-0

Ejemplares similares