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S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice
PURPOSE: To study the protective effects and underlying molecular mechanisms of SAMC on carbon tetrachloride (CCl(4))-induced acute hepatotoxicity in the mouse model. METHODS: Mice were intraperitoneally injected with CCl(4) (50 μl/kg; single dose) to induce acute hepatotoxicity with or without a 2-...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313023/ https://www.ncbi.nlm.nih.gov/pubmed/21681437 http://dx.doi.org/10.1007/s00394-011-0217-0 |