Multi-target siRNA based on DNMT3A/B homologous conserved region influences cell cycle and apoptosis of human prostate cancer cell line TSU-PR1

Abnormal genome hypermethylation participates in the tumorigenesis and development of prostate cancer. Prostate cancer cells highly express DNA methyltransferase 3 (DMNT3) family genes, essential for maintaining genome methylation. In the present study, multi-target siRNA, based on the homologous re...

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Detalles Bibliográficos
Autores principales: Du, Yue-feng, Liang, Liang, Shi, Ying, Long, Qing-zhi, Zeng, Jin, Wang, Xin-yang, He, Da-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313507/
https://www.ncbi.nlm.nih.gov/pubmed/22481891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313507/
https://www.ncbi.nlm.nih.gov/pubmed/22481891

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