Cargando…

Alzheimer's Disease and the Amyloid Cascade Hypothesis: A Critical Review

Since 1992, the amyloid cascade hypothesis has played the prominent role in explaining the etiology and pathogenesis of Alzheimer's disease (AD). It proposes that the deposition of β-amyloid (Aβ) is the initial pathological event in AD leading to the formation of senile plaques (SPs) and then t...

Descripción completa

Detalles Bibliográficos
Autor principal: Reitz, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313573/
https://www.ncbi.nlm.nih.gov/pubmed/22506132
http://dx.doi.org/10.1155/2012/369808