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Alzheimer's Disease and the Amyloid Cascade Hypothesis: A Critical Review
Since 1992, the amyloid cascade hypothesis has played the prominent role in explaining the etiology and pathogenesis of Alzheimer's disease (AD). It proposes that the deposition of β-amyloid (Aβ) is the initial pathological event in AD leading to the formation of senile plaques (SPs) and then t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313573/ https://www.ncbi.nlm.nih.gov/pubmed/22506132 http://dx.doi.org/10.1155/2012/369808 |