parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress

Parkinson's disease (PD) is characterized by movement disorders, including bradykinesia. Analysis of inherited, juvenile PD, identified several genes linked via a common pathway to mitochondrial dysfunction. In this study, we demonstrate that the larva of the Drosophila parkin mutant faithfully...

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Detalles Bibliográficos
Autores principales: Vincent, Amanda, Briggs, Laura, Chatwin, Griff F.J., Emery, Elizabeth, Tomlins, Rose, Oswald, Matt, Middleton, C. Adam, Evans, Gareth J.O., Sweeney, Sean T., Elliott, Christopher J.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313793/
https://www.ncbi.nlm.nih.gov/pubmed/22215442
http://dx.doi.org/10.1093/hmg/ddr609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313793/
https://www.ncbi.nlm.nih.gov/pubmed/22215442
http://dx.doi.org/10.1093/hmg/ddr609

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