Impaired parkin-mediated mitochondrial targeting to autophagosomes differentially contributes to tissue pathology in lysosomal storage diseases

Dysfunctional mitochondria are a well-known disease hallmark. The accumulation of aberrant mitochondria can alter cell homeostasis, thus resulting in tissue degeneration. Lysosomal storage disorders (LSDs) are a group of inherited diseases characterized by the buildup of undegraded material inside t...

Descripción completa

Detalles Bibliográficos
Autores principales: de Pablo-Latorre, Raquel, Saide, Assunta, Polishhuck, Elena V., Nusco, Edoardo, Fraldi, Alessandro, Ballabio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313794/
https://www.ncbi.nlm.nih.gov/pubmed/22215441
http://dx.doi.org/10.1093/hmg/ddr610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313794/
https://www.ncbi.nlm.nih.gov/pubmed/22215441
http://dx.doi.org/10.1093/hmg/ddr610

Ejemplares similares