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Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function
Mitochondrial dysfunction and oxidative stress have been implicated in the etiology of Parkinson's disease. Therefore, pathways controlling mitochondrial activity rapidly emerge as potential therapeutic targets. Here, we explore the neuronal response to prolonged overexpression of peroxisome pr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313800/ https://www.ncbi.nlm.nih.gov/pubmed/22246294 http://dx.doi.org/10.1093/hmg/ddr618 |