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Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function

Mitochondrial dysfunction and oxidative stress have been implicated in the etiology of Parkinson's disease. Therefore, pathways controlling mitochondrial activity rapidly emerge as potential therapeutic targets. Here, we explore the neuronal response to prolonged overexpression of peroxisome pr...

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Detalles Bibliográficos
Autores principales:	Ciron, C., Lengacher, S., Dusonchet, J., Aebischer, P., Schneider, B.L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313800/ https://www.ncbi.nlm.nih.gov/pubmed/22246294 http://dx.doi.org/10.1093/hmg/ddr618

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