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Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference

BACKGROUND: Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). However, serum bilirubin is also related with several potential confounders related to CVD, such as obesity. Mendelian randomization has been proposed as a method to address challenges to vali...

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Detalles Bibliográficos
Autores principales: McArdle, Patrick F, Whitcomb, Brian W, Tanner, Keith, Mitchell, Braxton D, Shuldiner, Alan R, Parsa, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313889/
https://www.ncbi.nlm.nih.gov/pubmed/22416852
http://dx.doi.org/10.1186/1471-2261-12-16