Cargando…
On the viability of Escherichia coli cells lacking DNA topoisomerase I
BACKGROUND: Manipulations of the DNA double helix during replication, transcription and other nucleic acid processing cause a change of DNA topology, which results in torsional stress. This stress is relaxed by DNA topoisomerases, a class of enzymes present in all domains of life. Negatively superco...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313902/ https://www.ncbi.nlm.nih.gov/pubmed/22373098 http://dx.doi.org/10.1186/1471-2180-12-26 |