Elucidating the identity of resistance mechanisms to prednisolone exposure in acute lymphoblastic leukemia cells through transcriptomic analysis: A computational approach

BACKGROUND: It has been shown previously that glucocorticoids exert a dual mechanism of action, entailing cytotoxic, mitogenic as well as cell proliferative and anti-apoptotic responses, in a dose-dependent manner on CCRF-CEM cells at 72 h. Early gene expression response implies a dose-dependent dua...

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Detalles Bibliográficos
Autores principales: Sifakis, Emmanouil G, Lambrou, George I, Prentza, Andriana, Vlahopoulos, Spiros, Koutsouris, Dimitris, Tzortzatou-Stathopoulou, Fotini, Chatziioannou, Aristotelis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313905/
https://www.ncbi.nlm.nih.gov/pubmed/22185641
http://dx.doi.org/10.1186/2043-9113-1-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313905/
https://www.ncbi.nlm.nih.gov/pubmed/22185641
http://dx.doi.org/10.1186/2043-9113-1-36

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