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X4 Human Immunodeficiency Virus Type 1 gp120 Promotes Human Hepatic Stellate Cell Activation and Collagen I Expression through Interactions with CXCR4

BACKGROUND & AIMS: Patients coinfected with HIV-1 and HCV develop more rapid liver fibrosis than patients monoinfected with HCV. HIV RNA levels correlate with fibrosis progression implicating HIV directly in the fibrotic process. While activated hepatic stellate cells (HSCs) express the 2 major...

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Detalles Bibliográficos
Autores principales: Hong, Feng, Saiman, Yedidya, Si, Chuanping, Mosoian, Arevik, Bansal, Meena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313947/
https://www.ncbi.nlm.nih.gov/pubmed/22479424
http://dx.doi.org/10.1371/journal.pone.0033659