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The Protein Partners of GTP Cyclohydrolase I in Rat Organs

OBJECTIVE: GTP cyclohydrolase I (GCH1) is the rate-limiting enzyme for tetrahydrobiopterin biosynthesis and has been shown to be a promising therapeutic target in ischemic heart disease, hypertension, atherosclerosis and diabetes. The endogenous GCH1-interacting partners have not been identified. He...

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Detalles Bibliográficos
Autores principales: Du, Jianhai, Teng, Ru-Jeng, Lawrence, Matt, Guan, Tongju, Xu, Hao, Ge, Ying, Shi, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313957/
https://www.ncbi.nlm.nih.gov/pubmed/22479495
http://dx.doi.org/10.1371/journal.pone.0033991