Cargando…

Mtss1 Promotes Cell-Cell Junction Assembly and Stability through the Small GTPase Rac1

Cell-cell junctions are an integral part of epithelia and are often disrupted in cancer cells during epithelial-to-mesenchymal transition (EMT), which is a main driver of metastatic spread. We show here that Metastasis suppressor-1 (Mtss1; Missing in Metastasis, MIM), a member of the IMD-family of p...

Descripción completa

Detalles Bibliográficos
Autores principales: Dawson, John C., Bruche, Susann, Spence, Heather J., Braga, Vania M. M., Machesky, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313965/
https://www.ncbi.nlm.nih.gov/pubmed/22479308
http://dx.doi.org/10.1371/journal.pone.0031141