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Isosteviol Has Beneficial Effects on Palmitate-Induced α-Cell Dysfunction and Gene Expression
BACKGROUND: Long-term exposure to high levels of fatty acids impairs insulin secretion and exaggerates glucagon secretion. The aim of this study was to explore if the antihyperglycemic agent, Isosteviol (ISV), is able to counteract palmitate-induced α-cell dysfunction and to influence α-cell gene ex...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313988/ https://www.ncbi.nlm.nih.gov/pubmed/22479612 http://dx.doi.org/10.1371/journal.pone.0034361 |