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Isosteviol Has Beneficial Effects on Palmitate-Induced α-Cell Dysfunction and Gene Expression

BACKGROUND: Long-term exposure to high levels of fatty acids impairs insulin secretion and exaggerates glucagon secretion. The aim of this study was to explore if the antihyperglycemic agent, Isosteviol (ISV), is able to counteract palmitate-induced α-cell dysfunction and to influence α-cell gene ex...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoping, Hermansen, Kjeld, Xiao, Jianzhong, Bystrup, Sara Kjaergaard, O'Driscoll, Lorraine, Jeppesen, Per Bendix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313988/
https://www.ncbi.nlm.nih.gov/pubmed/22479612
http://dx.doi.org/10.1371/journal.pone.0034361