C-Terminal Clipping of Chemokine CCL1/I-309 Enhances CCR8-Mediated Intracellular Calcium Release and Anti-Apoptotic Activity

Carboxypeptidase M (CPM) targets the basic amino acids arginine and lysine present at the C-terminus of peptides or proteins. CPM is thought to be involved in inflammatory processes. This is corroborated by CPM-mediated trimming and modulation of inflammatory factors, and expression of the protease...

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Detalles Bibliográficos
Autores principales: Denis, Catherine, Deiteren, Kathleen, Mortier, Anneleen, Tounsi, Amel, Fransen, Erik, Proost, Paul, Renauld, Jean-Christophe, Lambeir, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313992/
https://www.ncbi.nlm.nih.gov/pubmed/22479563
http://dx.doi.org/10.1371/journal.pone.0034199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313992/
https://www.ncbi.nlm.nih.gov/pubmed/22479563
http://dx.doi.org/10.1371/journal.pone.0034199

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