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C-Terminal Clipping of Chemokine CCL1/I-309 Enhances CCR8-Mediated Intracellular Calcium Release and Anti-Apoptotic Activity
Carboxypeptidase M (CPM) targets the basic amino acids arginine and lysine present at the C-terminus of peptides or proteins. CPM is thought to be involved in inflammatory processes. This is corroborated by CPM-mediated trimming and modulation of inflammatory factors, and expression of the protease...
Autores principales: | Denis, Catherine, Deiteren, Kathleen, Mortier, Anneleen, Tounsi, Amel, Fransen, Erik, Proost, Paul, Renauld, Jean-Christophe, Lambeir, Anne-Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313992/ https://www.ncbi.nlm.nih.gov/pubmed/22479563 http://dx.doi.org/10.1371/journal.pone.0034199 |
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