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Dynamic Regulation of Tgf-B Signaling by Tif1γ: A Computational Approach

TIF1γ (Transcriptional Intermediary Factor 1 γ) has been implicated in Smad-dependent signaling by Transforming Growth Factor beta (TGF-β). Paradoxically, TIF1γ functions both as a transcriptional repressor or as an alternative transcription factor that promotes TGF-β signaling. Using ordinary diffe...

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Detalles Bibliográficos
Autores principales: Andrieux, Geoffroy, Fattet, Laurent, Le Borgne, Michel, Rimokh, Ruth, Théret, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314286/
https://www.ncbi.nlm.nih.gov/pubmed/22461896
http://dx.doi.org/10.1371/journal.pone.0033761