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A Broadly Cross-Reactive Monoclonal Antibody Against an Epitope on the N-terminus of Meningococcal fHbp

Meningococcal factor H binding protein (fHbp) is an important vaccine antigen for prevention of disease caused by capsular group B strains. The protein has been sub-classified into three variant groups. Most anti-fHbp antibodies are variant group-specific and recognize epitopes on the C-terminal dom...

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Detalles Bibliográficos
Autores principales: Vu, David M., Pajon, Rolando, Reason, Donald C., Granoff, Dan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314305/
https://www.ncbi.nlm.nih.gov/pubmed/22461972
http://dx.doi.org/10.1038/srep00341