Cargando…

A Broadly Cross-Reactive Monoclonal Antibody Against an Epitope on the N-terminus of Meningococcal fHbp

Meningococcal factor H binding protein (fHbp) is an important vaccine antigen for prevention of disease caused by capsular group B strains. The protein has been sub-classified into three variant groups. Most anti-fHbp antibodies are variant group-specific and recognize epitopes on the C-terminal dom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vu, David M., Pajon, Rolando, Reason, Donald C., Granoff, Dan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314305/ https://www.ncbi.nlm.nih.gov/pubmed/22461972 http://dx.doi.org/10.1038/srep00341

Ejemplares similares

ERRATUM: A Broadly Cross-Reactive Monoclonal Antibody Against an Epitope on the N-terminus of Meningococcal fHbp
por: Vu, David M., et al.
Publicado: (2013)

Human Factor H (FH) Impairs Protective Meningococcal Anti-FHbp Antibody Responses and the Antibodies Enhance FH Binding
por: Costa, Isabella, et al.
Publicado: (2014)

Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp
por: López-Sagaseta, Jacinto, et al.
Publicado: (2018)

Monoclonal Antibodies to Meningococcal Factor H Binding Protein with Overlapping Epitopes and Discordant Functional Activity
por: Giuntini, Serena, et al.
Publicado: (2012)

An Analysis of the Sequence Variability of Meningococcal fHbp, NadA and NHBA over a 50-Year Period in the Netherlands
por: Bambini, Stefania, et al.
Publicado: (2013)

4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp
por: Veggi, Daniele, et al.
Publicado: (2020)

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1
por: Marini, Arianna, et al.
Publicado: (2017)

Thermoregulation of Meningococcal fHbp, an Important Virulence Factor and Vaccine Antigen, Is Mediated by Anti-ribosomal Binding Site Sequences in the Open Reading Frame
por: Loh, Edmund, et al.
Publicado: (2016)

A Newly-Identified Polymorphism in Rhesus Macaque Complement Factor H Modulates Binding Affinity for Meningococcal FHbp
por: Konar, Monica, et al.
Publicado: (2015)

The effect of iron availability on transcription of the Neisseria meningitidis fHbp gene varies among clonal complexes
por: Sanders, Holly, et al.
Publicado: (2012)

Selection of diverse strains to assess broad coverage of the bivalent FHbp meningococcal B vaccine
por: Harris, Shannon L., et al.
Publicado: (2020)

Neisseria meningitidis porA, fetA and fHbp gene distribution in Western Australia 2000 to 2011
por: Boan, Peter, et al.
Publicado: (2014)

Mutant Native Outer Membrane Vesicles Combined with a Serogroup A Polysaccharide Conjugate Vaccine for Prevention of Meningococcal Epidemics in Africa
por: Pajon, Rolando, et al.
Publicado: (2013)

Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup C Neisseria meningitidis isolate from cerebrospinal fluid of a patient with invasive meningococcal disease
por: Facchetti, Alessandra, et al.
Publicado: (2021)

Meningococcal Factor H Binding Proteins in Epidemic Strains from Africa: Implications for Vaccine Development
por: Pajon, Rolando, et al.
Publicado: (2011)

A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine
por: Beernink, Peter T., et al.
Publicado: (2019)

The Effect of Human Factor H on Immunogenicity of Meningococcal Native Outer Membrane Vesicle Vaccines with Over-Expressed Factor H Binding Protein
por: Beernink, Peter T., et al.
Publicado: (2012)

Commentary: Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates
por: Liberator, Paul, et al.
Publicado: (2020)

Identification of a Novel Linear B-Cell Epitope of HbpA Protein from Glaesserella parasuis Using Monoclonal Antibody
por: Liu, Geyan, et al.
Publicado: (2023)

‘Be on the TEAM’ Study (Teenagers Against Meningitis): protocol for a controlled clinical trial evaluating the impact of 4CMenB or MenB-fHbp vaccination on the pharyngeal carriage of meningococci in adolescents
por: Carr, Jeremy, et al.
Publicado: (2020)

Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates
por: da Silva, Ronni A. G., et al.
Publicado: (2019)

Updated Recommendations for Use of MenB-FHbp Serogroup B Meningococcal Vaccine — Advisory Committee on Immunization Practices, 2016
por: Patton, Monica E., et al.
Publicado: (2017)

Corrigendum: Variant Signal Peptides of Vaccine Antigen, FHbp, Impair Processing Affecting Surface Localization and Antibody-Mediated Killing in Most Meningococcal Isolates
por: da Silva, Ronni A. G., et al.
Publicado: (2020)

Meningococcal B vaccine antigen FHbp variants among disease-causing Neisseria meningitidis B isolates, Italy, 2014–2017
por: Carannante, Anna, et al.
Publicado: (2020)

Sex, Age, and Race Effects on Immunogenicity of MenB-FHbp, A Bivalent Meningococcal B Vaccine: Pooled Evaluation of Clinical Trial Data
por: Beeslaar, Johannes, et al.
Publicado: (2020)

A Mutant Library Approach to Identify Improved Meningococcal Factor H Binding Protein Vaccine Antigens
por: Konar, Monica, et al.
Publicado: (2015)

MenB-FHbp Vaccine Protects Against Diverse Meningococcal Strains in Adolescents and Young Adults: Post Hoc Analysis of Two Phase 3 Studies
por: Beeslaar, Johannes, et al.
Publicado: (2020)

Functional Analysis of the Human Antibody Response to Meningococcal Factor H Binding Protein
por: Beernink, Peter T., et al.
Publicado: (2015)

2722. Effects of Sex, Age, and Race on Immunogenicity of MenB-FHbp, a Bivalent Meningococcal B Vaccine: A Pooled Evaluation of Clinical Trial Data
por: Beeslaar, Johannes, et al.
Publicado: (2019)

Broadly Protective Neuraminidase-Based Influenza Vaccines and Monoclonal Antibodies: Target Epitopes and Mechanisms of Action
por: Abbadi, Nada, et al.
Publicado: (2023)

Anti-Factor H Antibody Reactivity in Young Adults Vaccinated with a Meningococcal Serogroup B Vaccine Containing Factor H Binding Protein
por: Sharkey, Kelsey, et al.
Publicado: (2019)

Characterization of a broadly cross reactive tetravalent human monoclonal antibody, recognizing conformational epitopes in receptor binding domain of SARS-CoV-2
por: Garg, Sonal, et al.
Publicado: (2022)

Molecular characterization of invasive Neisseria meningitidis isolates collected in Lithuania (2009-2019) and estimation of serogroup B meningococcal vaccine 4CMenB and MenB-Fhbp coverage
por: Sereikaitė, Emilija, et al.
Publicado: (2023)

Identification of a B-cell antigenic epitope at the N-terminus of SARS-CoV M protein and characterization of monoclonal antibody against the protein
por: Qian, Chao, et al.
Publicado: (2006)

The Epitope and Neutralization Mechanism of AVFluIgG01, a Broad-Reactive Human Monoclonal Antibody against H5N1 Influenza Virus
por: Cao, Zhiliang, et al.
Publicado: (2012)

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody
por: Gupta, Nimesh, et al.
Publicado: (2015)

Human autoantibody-reactive epitopes of SS-B/La are highly conserved in comparison with epitopes recognized by murine monoclonal antibodies
Publicado: (1987)

Broadly protective murine monoclonal antibodies against influenza B virus target highly conserved neuraminidase epitopes
por: Wohlbold, Teddy John, et al.
Publicado: (2017)

A physician’s guide to the 2-dose schedule of MenB-FHbp vaccine
por: McDaniel, Angee, et al.
Publicado: (2019)

Generation and characterization of monoclonal antibodies against the N-terminus of alpha-2-antiplasmin
por: Abdul, Shiraazkhan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5ha0of2jpq3dgoqi8c7s7hel9m