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Candesartan Cilexetil Improves Angiotensin II Type 2 Receptor–Mediated Neurite Outgrowth via the PI3K-Akt Pathway in Fructose-Induced Insulin-Resistant Rats

We have shown previously that stimulation of the angiotensin II type 2 receptor (AT(2)R) results in nerve facilitation. In this study, we determined the capacity of candesartan to correct expression patterns characteristic of neuropathy and AT(2)R-mediated neurite outgrowth in the fructose-induced i...

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Detalles Bibliográficos
Autores principales: Hashikawa-Hobara, Narumi, Hashikawa, Naoya, Inoue, Yusuke, Sanda, Hitomi, Zamami, Yoshito, Takatori, Shingo, Kawasaki, Hiromu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314356/
https://www.ncbi.nlm.nih.gov/pubmed/22357959
http://dx.doi.org/10.2337/db11-1468