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Candesartan Cilexetil Improves Angiotensin II Type 2 Receptor–Mediated Neurite Outgrowth via the PI3K-Akt Pathway in Fructose-Induced Insulin-Resistant Rats
We have shown previously that stimulation of the angiotensin II type 2 receptor (AT(2)R) results in nerve facilitation. In this study, we determined the capacity of candesartan to correct expression patterns characteristic of neuropathy and AT(2)R-mediated neurite outgrowth in the fructose-induced i...
Autores principales: | Hashikawa-Hobara, Narumi, Hashikawa, Naoya, Inoue, Yusuke, Sanda, Hitomi, Zamami, Yoshito, Takatori, Shingo, Kawasaki, Hiromu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314356/ https://www.ncbi.nlm.nih.gov/pubmed/22357959 http://dx.doi.org/10.2337/db11-1468 |
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