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Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes

Recent studies reveal a strong relationship between reduced mitochondrial content and insulin resistance in human skeletal muscle, although the underlying factors responsible for this association remain unknown. To address this question, we analyzed muscle biopsy samples from young, lean, insulin re...

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Detalles Bibliográficos
Autores principales: Morino, Katsutaro, Petersen, Kitt Falk, Sono, Saki, Choi, Cheol Soo, Samuel, Varman T., Lin, Aiping, Gallo, Amy, Zhao, Hongyu, Kashiwagi, Atsunori, Goldberg, Ira J., Wang, Hong, Eckel, Robert H., Maegawa, Hiroshi, Shulman, Gerald I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314372/
https://www.ncbi.nlm.nih.gov/pubmed/22368174
http://dx.doi.org/10.2337/db11-1391