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A methodology for detecting the orthology signal in a PPI network at a functional complex level

BACKGROUND: Stable evolutionary signal has been observed in a yeast protein-protein interaction (PPI) network. These finding suggests more connected regions of a PPI network to be potential mediators of evolutionary information. Because more connected regions of PPI networks contain functional compl...

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Detalles Bibliográficos
Autores principales: Jancura, Pavol, Mavridou, Eleftheria, Carrillo-de Santa Pau, Enrique, Marchiori, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314571/
https://www.ncbi.nlm.nih.gov/pubmed/22759423
http://dx.doi.org/10.1186/1471-2105-13-S10-S18