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Involvement of Hypoxia-Inducible Factor-1 in the Inflammatory Responses of Human LAD2 Mast Cells and Basophils

We recently showed that hypoxia-inducible factor 1 (HIF-1) plays a crucial role in the pro-allergic functions of human basophils by transcriptional control of energy metabolism via glycolysis as well as directly triggering expression of the angiogenic cytokine vascular endothelium growth factor (VEG...

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Detalles Bibliográficos
Autores principales: Sumbayev, Vadim V., Yasinska, Inna, Oniku, Abraham E., Streatfield, Claire L., Gibbs, Bernhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314605/
https://www.ncbi.nlm.nih.gov/pubmed/22470546
http://dx.doi.org/10.1371/journal.pone.0034259