Crystal Structures of the Tetratricopeptide Repeat Domains of Kinesin Light Chains: Insight into Cargo Recognition Mechanisms

Kinesin-1 transports various cargos along the axon by interacting with the cargos through its light chain subunit. Kinesin light chains (KLC) utilize its tetratricopeptide repeat (TPR) domain to interact with over 10 different cargos. Despite a high sequence identity between their TPR domains (87%),...

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Detalles Bibliográficos
Autores principales: Zhu, Haizhong, Lee, Han Youl, Tong, Yufeng, Hong, Bum-Soo, Kim, Kyung-Phil, Shen, Yang, Lim, Kyung Jik, Mackenzie, Farrell, Tempel, Wolfram, Park, Hee-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314626/
https://www.ncbi.nlm.nih.gov/pubmed/22470497
http://dx.doi.org/10.1371/journal.pone.0033943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314626/
https://www.ncbi.nlm.nih.gov/pubmed/22470497
http://dx.doi.org/10.1371/journal.pone.0033943

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