Cargando…

Crystal Structures of the Tetratricopeptide Repeat Domains of Kinesin Light Chains: Insight into Cargo Recognition Mechanisms

Kinesin-1 transports various cargos along the axon by interacting with the cargos through its light chain subunit. Kinesin light chains (KLC) utilize its tetratricopeptide repeat (TPR) domain to interact with over 10 different cargos. Despite a high sequence identity between their TPR domains (87%),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Haizhong, Lee, Han Youl, Tong, Yufeng, Hong, Bum-Soo, Kim, Kyung-Phil, Shen, Yang, Lim, Kyung Jik, Mackenzie, Farrell, Tempel, Wolfram, Park, Hee-Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314626/ https://www.ncbi.nlm.nih.gov/pubmed/22470497 http://dx.doi.org/10.1371/journal.pone.0033943

Ejemplares similares

Protein Tetratricopeptide Repeat and the Companion Non-tetratricopeptide Repeat Helices: Bioinformatic Analysis of Interhelical Interactions
por: Barik, Sailen
Publicado: (2019)

Intrinsic Disorder in Tetratricopeptide Repeat Proteins
por: Van Bibber, Nathan W., et al.
Publicado: (2020)

Crystal Structure of the N-Acetylmannosamine Kinase Domain of GNE
por: Tong, Yufeng, et al.
Publicado: (2009)

Differential Impact of Tetratricopeptide Repeat Proteins on the Steroid Hormone Receptors
por: Schülke, Jan-Philip, et al.
Publicado: (2010)

Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors
por: Pernigo, Stefano, et al.
Publicado: (2018)

Characterization of Tetratricopeptide Repeat-Containing Proteins Critical for Cilia Formation and Function
por: Xu, Yanan, et al.
Publicado: (2015)

Structural and Functional Insights into Small, Glutamine-Rich, Tetratricopeptide Repeat Protein Alpha
por: Roberts, Joanna D., et al.
Publicado: (2015)

Identification of Kinesin-1 Cargos Using Fluorescence Microscopy
por: Lee, Clement M.
Publicado: (2016)

Multiple kinesins induce tension for smooth cargo transport
por: Tjioe, Marco, et al.
Publicado: (2019)

The tetratricopeptide repeat-containing protein slow green1 is required for chloroplast development in Arabidopsis
por: Hu, Zhihong, et al.
Publicado: (2014)

Tetratricopeptide Repeat Domain 9A Negatively Regulates Estrogen Receptor Alpha Activity
por: Shrestha, Smeeta, et al.
Publicado: (2015)

Tetratricopeptide repeat domain 9A modulates anxiety-like behavior in female mice
por: Lim, Lee Wei, et al.
Publicado: (2016)

Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination
por: Onyango, David O., et al.
Publicado: (2016)

Chicken Interferon-induced Protein with Tetratricopeptide Repeats 5 Antagonizes Replication of RNA Viruses
por: Santhakumar, Diwakar, et al.
Publicado: (2018)

Novel Mutations of the Tetratricopeptide Repeat Domain 7A Gene and Phenotype/Genotype Comparison
por: Lien, Reyin, et al.
Publicado: (2017)

Kinesin-1 captures RNA cargo in its adaptable coils
por: Cross, Jessica A., et al.
Publicado: (2021)

Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport
por: Qiu, Rongde, et al.
Publicado: (2022)

Tetratricopeptide repeat domain 9A is an interacting protein for tropomyosin Tm5NM-1
por: Cao, Shenglan, et al.
Publicado: (2008)

Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure
por: El-Daher, Marie-Therese, et al.
Publicado: (2018)

Conformational Change of Tetratricopeptide Repeats Region Triggers Activation of Phytochrome-Associated Protein Phosphatase 5
por: von Horsten, Silke, et al.
Publicado: (2021)

Lemur tyrosine kinase-2 signalling regulates kinesin light chain-2 phosphorylation and binding of Smad2 cargo
por: Manser, Catherine, et al.
Publicado: (2011)

Cargo of Kinesin Identified as Jip Scaffolding Proteins and Associated Signaling Molecules
por: Verhey, Kristen J., et al.
Publicado: (2001)

Cargo diffusion shortens single-kinesin runs at low viscous drag
por: Wilson, John O., et al.
Publicado: (2019)

Inducible manipulation of motor–cargo interaction using engineered kinesin motors
por: Hummel, Jessica J. A., et al.
Publicado: (2021)

The physiological cargo adaptor of kinesin-2 functions as an evolutionary conserved lockpick
por: Cleetus, Augustine, et al.
Publicado: (2022)

Defective Kinesin Heavy Chain Behavior in Mouse Kinesin Light Chain Mutants
por: Rahman, Amena, et al.
Publicado: (1999)

Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor
por: Lisa, María-Natalia, et al.
Publicado: (2019)

Essential Roles of the Linker Sequence Between Tetratricopeptide Repeat Motifs of Ethylene Overproduction 1 in Ethylene Biosynthesis
por: An, Chuanjing, et al.
Publicado: (2021)

Interferon-induced protein with tetratricopeptide repeats 3 may be a key factor in primary biliary cholangitis
por: Sasaki, Motoko, et al.
Publicado: (2021)

The Interferon-Induced Protein with Tetratricopeptide Repeats Repress Influenza Virus Infection by Inhibiting Viral RNA Synthesis
por: Zhu, Zhengyu, et al.
Publicado: (2023)

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY
por: Hong, Bum Soo, et al.
Publicado: (2010)

Molecular Motor Proteins of the Kinesin Superfamily Proteins (KIFs): Structure, Cargo and Disease
por: Seog, Dae-Hyun, et al.
Publicado: (2004)

Hook is an adapter that coordinates kinesin-3 and dynein cargo attachment on early endosomes
por: Bielska, Ewa, et al.
Publicado: (2014)

Cholesterol in the cargo membrane amplifies tau inhibition of kinesin-1-based transport
por: Li, Qiaochu, et al.
Publicado: (2023)

Presynaptic Precursor Vesicles—Cargo, Biogenesis, and Kinesin-Based Transport across Species
por: Petzoldt, Astrid G.
Publicado: (2023)

LATS1 and LATS2 Phosphorylate CDC26 to Modulate Assembly of the Tetratricopeptide Repeat Subcomplex of APC/C
por: Masuda, Kenta, et al.
Publicado: (2015)

Tetratricopeptide repeat domain 3 overexpression tends to form aggregates and inhibit ubiquitination and degradation of DNA polymerase γ
por: Gong, Yueqing, et al.
Publicado: (2017)

Transmembrane and Tetratricopeptide Repeat Containing 4 Is a Novel Diagnostic Marker for Prostate Cancer with High Specificity and Sensitivity
por: Makboul, Rania, et al.
Publicado: (2021)

Tetratricopeptide repeat domain 9A knockout induces social anxiety and impairs offense behaviors in female mice
por: Yu, Wing Shan, et al.
Publicado: (2022)

dTtc1, a conserved tetratricopeptide repeat protein, is required for maturation of Drosophila egg chambers via its role in stabilizing electron transport chain components
por: Neiswender, Hannah, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l1lgifs6fimnnph0om1uk4dofu