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AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland

BACKGROUND: Narcolepsy is a chronic sleep disorder with strong genetic predisposition causing excessive daytime sleepiness and cataplexy. A sudden increase in childhood narcolepsy was observed in Finland soon after pandemic influenza epidemic and vaccination with ASO3-adjuvanted Pandemrix. No increa...

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Detalles Bibliográficos
Autores principales: Nohynek, Hanna, Jokinen, Jukka, Partinen, Markku, Vaarala, Outi, Kirjavainen, Turkka, Sundman, Jonas, Himanen, Sari-Leena, Hublin, Christer, Julkunen, Ilkka, Olsén, Päivi, Saarenpää-Heikkilä, Outi, Kilpi, Terhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314666/
https://www.ncbi.nlm.nih.gov/pubmed/22470453
http://dx.doi.org/10.1371/journal.pone.0033536