Cargando…

AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland

BACKGROUND: Narcolepsy is a chronic sleep disorder with strong genetic predisposition causing excessive daytime sleepiness and cataplexy. A sudden increase in childhood narcolepsy was observed in Finland soon after pandemic influenza epidemic and vaccination with ASO3-adjuvanted Pandemrix. No increa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nohynek, Hanna, Jokinen, Jukka, Partinen, Markku, Vaarala, Outi, Kirjavainen, Turkka, Sundman, Jonas, Himanen, Sari-Leena, Hublin, Christer, Julkunen, Ilkka, Olsén, Päivi, Saarenpää-Heikkilä, Outi, Kilpi, Terhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314666/ https://www.ncbi.nlm.nih.gov/pubmed/22470453 http://dx.doi.org/10.1371/journal.pone.0033536

Ejemplares similares

No Serological Evidence of Influenza A H1N1pdm09 Virus Infection as a Contributing Factor in Childhood Narcolepsy after Pandemrix Vaccination Campaign in Finland
por: Melén, Krister, et al.
Publicado: (2013)

Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk
por: Vaarala, Outi, et al.
Publicado: (2014)

Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland
por: Partinen, Markku, et al.
Publicado: (2012)

No evidence of autoimmunity to human OX(1) or OX(2) orexin receptors in Pandemrix-vaccinated narcoleptic children
por: Melén, Krister, et al.
Publicado: (2020)

Effectiveness of Pandemic and Seasonal Influenza Vaccines in Preventing Laboratory-Confirmed Influenza in Adults: A Clinical Cohort Study during Epidemic Seasons 2009–2010 and 2010–2011 in Finland
por: Syrjänen, Ritva K., et al.
Publicado: (2014)

Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1
por: Vuorela, A., et al.
Publicado: (2021)

Neuronal Antibodies in Children with or without Narcolepsy following H1N1-AS03 Vaccination
por: Thebault, Simon, et al.
Publicado: (2015)

Sleep disturbances and depressive and anxiety symptoms during pregnancy: associations with delivery and newborn health
por: Peltonen, Hilla, et al.
Publicado: (2022)

High-dose electronic media use in five-year-olds and its association with their psychosocial symptoms: a cohort study
por: Niiranen, Janette, et al.
Publicado: (2021)

Impact of ten-valent pneumococcal conjugate vaccine on pneumonia in Finnish children in a nation-wide population-based study
por: Palmu, Arto A., et al.
Publicado: (2017)

Adjuvanted AH1N1 influenza vaccine precipitating the appearance of narcolepsy()
por: Boquete Castro, A., et al.
Publicado: (2021)

The Effects of Genetic Background for Diurnal Preference on Sleep Development in Early Childhood
por: Morales-Muñoz, Isabel, et al.
Publicado: (2021)

Attention-Deficit/Hyperactivity Disorder Patients May Have Undiagnosed Narcolepsy
por: Wilenius, Lukas, et al.
Publicado: (2020)

Psychosis in Patients with Narcolepsy as an Adverse Effect of Sodium Oxybate
por: Sarkanen, Tomi, et al.
Publicado: (2014)

Effectiveness of the live attenuated and the inactivated influenza vaccine in two-year-olds – a nationwide cohort study Finland, influenza season 2015/16
por: Nohynek, Hanna, et al.
Publicado: (2016)

Establishing and maintaining the National Vaccination Register in Finland
por: Baum, Ulrike, et al.
Publicado: (2017)

Paternal perinatal stress is associated with children's emotional problems at 2 years
por: Challacombe, Fiona L., et al.
Publicado: (2022)

Variants in calcium voltage-gated channel subunit Alpha1 C-gene (CACNA1C) are associated with sleep latency in infants
por: Kantojärvi, Katri, et al.
Publicado: (2017)

The relationship between orexin levels and blood pressure changes in patients with narcolepsy
por: Sieminski, Mariusz, et al.
Publicado: (2017)

Incidence of sinus thrombosis with thrombocytopenia—A nation-wide register study
por: Hovi, Petteri, et al.
Publicado: (2023)

Accuracy of Actigraphy Compared to Concomitant Ambulatory Polysomnography in Narcolepsy and Other Sleep Disorders
por: Alakuijala, Anniina, et al.
Publicado: (2021)

Obstructive sleep apnea is position dependent in young infants
por: Kukkola, Hanna-Leena, et al.
Publicado: (2022)

Prenatal and Postnatal Predictive Factors for Children’s Inattentive and Hyperactive Symptoms at 5 Years of Age: The Role of Early Family-related Factors
por: Huhdanpää, Hanna, et al.
Publicado: (2020)

The “Perfect Storm” for Type 1 Diabetes: The Complex Interplay Between Intestinal Microbiota, Gut Permeability, and Mucosal Immunity
por: Vaarala, Outi, et al.
Publicado: (2008)

Hypothetical model of perceived adherence to treatment among patients with coronary heart disease after a percutaneous coronary intervention
por: Kähkönen, Outi, et al.
Publicado: (2019)

Sleep Difficulties in Infancy Are Associated with Symptoms of Inattention and Hyperactivity at the Age of 5 Years: A Longitudinal Study
por: Huhdanpää, Hanna, et al.
Publicado: (2019)

Signaled night awakening and its association with social information processing and socio-emotional development across the first two years
por: Mäkelä, Tiina E, et al.
Publicado: (2021)

Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy
por: Luo, Guo, et al.
Publicado: (2018)

High vaccine effectiveness against severe COVID-19 in the elderly in Finland before and after the emergence of Omicron
por: Baum, Ulrike, et al.
Publicado: (2022)

Correction to: Caffeine is a respiratory stimulant without effect on sleep in the short-term in late-preterm infants
por: Seppä-Moilanen, Maija, et al.
Publicado: (2022)

Caffeine is a respiratory stimulant without effect on sleep in the short-term in late-preterm infants
por: Seppä-Moilanen, Maija, et al.
Publicado: (2021)

Supplemental Oxygen Treats Periodic Breathing without Effects on Sleep in Late-Preterm Infants
por: Seppä-Moilanen, Maija, et al.
Publicado: (2022)

Clinical and polysomnographic course of childhood narcolepsy with cataplexy
por: Pizza, Fabio, et al.
Publicado: (2013)

Parent-reported early sleep problems and internalising, externalising and dysregulation symptoms in toddlers
por: Morales-Muñoz, Isabel, et al.
Publicado: (2020)

Lactose inhibits regulatory T-cell-mediated suppression of effector T-cell interferon-γ and IL-17 production
por: Paasela, Monika, et al.
Publicado: (2014)

Exploring the clinical features of narcolepsy type 1 versus narcolepsy type 2 from European Narcolepsy Network database with machine learning
por: Zhang, Zhongxing, et al.
Publicado: (2018)

No evidence for activation of T(H)1 or T(H)17 pathways in unstimulated peripheral blood mononuclear cells from children with β-cell autoimmunity or T1D
por: Walldén, Jenny, et al.
Publicado: (2008)

Exposure to sewage water and the development of allergic manifestations in Finnish children
por: Kujansuu, Eila, et al.
Publicado: (2019)

Narcolepsy
por: Maclachlan, T. Kay
Publicado: (1930)

Narcolepsy
Publicado: (1929)

Cannot write session to /tmp/vufind_sessions/sess_c1u5kd29gvs9lqhe99oejv62le