Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts

Interstitial fibrosis is an inevitable outcome of all kinds of progressive chronic kidney disease (CKD). Emerging data indicate that rapamycin can ameliorate kidney fibrosis by reducing the interstitial infiltrates and accumulation of extra cellular matrix (ECM). However, the cellular mechanism that...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Guochun, Chen, Huihui, Wang, Chang, Peng, Youming, Sun, Lin, Liu, Hong, Liu, Fuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314672/
https://www.ncbi.nlm.nih.gov/pubmed/22470459
http://dx.doi.org/10.1371/journal.pone.0033626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314672/
https://www.ncbi.nlm.nih.gov/pubmed/22470459
http://dx.doi.org/10.1371/journal.pone.0033626

Ejemplares similares