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The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancer

BACKGROUND: The chemokine CXCL12 and its cognate receptor, CXCR4, have been implicated in numerous tumour types where expression promotes tumour growth, angiogenesis, metastasis and suppresses tumour immunity. METHODS: Using a tissue microarray of 289 primary ovarian cancers coupled to a comprehensi...

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Detalles Bibliográficos
Autores principales: Popple, A, Durrant, L G, Spendlove, I, Rolland, P, Scott, I V, Deen, S, Ramage, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314783/
https://www.ncbi.nlm.nih.gov/pubmed/22415233
http://dx.doi.org/10.1038/bjc.2012.49