Cargando…

The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancer

BACKGROUND: The chemokine CXCL12 and its cognate receptor, CXCR4, have been implicated in numerous tumour types where expression promotes tumour growth, angiogenesis, metastasis and suppresses tumour immunity. METHODS: Using a tissue microarray of 289 primary ovarian cancers coupled to a comprehensi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Popple, A, Durrant, L G, Spendlove, I, Rolland, P, Scott, I V, Deen, S, Ramage, J M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314783/ https://www.ncbi.nlm.nih.gov/pubmed/22415233 http://dx.doi.org/10.1038/bjc.2012.49

Ejemplares similares

Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity
por: Gooden, M J M, et al.
Publicado: (2014)

Expression of the chemokine CXCL14 in the tumour stroma is an independent marker of survival in breast cancer
por: Sjöberg, Elin, et al.
Publicado: (2016)

Ectopic expression of the chemokine CXCL17 in colon cancer cells
por: Ohlsson, Lina, et al.
Publicado: (2016)

Survivin is an independent predictor of short-term survival in poor prognostic breast cancer patients
por: Hinnis, A R, et al.
Publicado: (2007)

High mobility group protein B1 is a predictor of poor survival in ovarian cancer
por: Machado, Lee R., et al.
Publicado: (2017)

Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients
por: Panse, J, et al.
Publicado: (2008)

TGFBI expression is an independent predictor of survival in adjuvant-treated lung squamous cell carcinoma patients
por: Pajares, M J, et al.
Publicado: (2014)

High mesothelin correlates with chemoresistance and poor survival in epithelial ovarian carcinoma
por: Cheng, W-F, et al.
Publicado: (2009)

Oncogenic CXCL10 signalling drives metastasis development and poor clinical outcome
por: Wightman, S C, et al.
Publicado: (2015)

The proportion of tumour cells is an independent predictor for survival in colorectal cancer patients
por: West, N P, et al.
Publicado: (2010)

Erythrocyte sedimentation rate and anaemia are independent predictors of survival in patients with clear cell renal cell carcinoma
por: Choi, Y, et al.
Publicado: (2013)

Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients
por: Hosono, S, et al.
Publicado: (2007)

C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma
por: Mahner, S, et al.
Publicado: (2008)

High bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes
por: Cheng, C-L, et al.
Publicado: (2011)

CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma
por: Werner, Thomas A, et al.
Publicado: (2017)

Increased expression of ALCAM/CD166 in pancreatic cancer is an independent prognostic marker for poor survival and early tumour relapse
por: Kahlert, C, et al.
Publicado: (2009)

Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma
por: Arnold, J M, et al.
Publicado: (2005)

High levels of cleaved caspase-3 in colorectal tumour stroma predict good survival
por: Noble, P, et al.
Publicado: (2013)

Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival
por: Herath, N I, et al.
Publicado: (2009)

Δ133p53 is an independent prognostic marker in p53 mutant advanced serous ovarian cancer
por: Hofstetter, G, et al.
Publicado: (2011)

Minichromosome maintenance protein 6, a proliferation marker superior to Ki-67 and independent predictor of survival in patients with mantle cell lymphoma
por: Schrader, C, et al.
Publicado: (2005)

High expression of CXCR4 may predict poor survival in resected pancreatic adenocarcinoma
por: Maréchal, R, et al.
Publicado: (2009)

Cortactin expression predicts poor survival in laryngeal carcinoma
por: Gibcus, J H, et al.
Publicado: (2008)

Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer
por: Larsson, A, et al.
Publicado: (2011)

Expression of CC chemokine receptor 7 in tonsillar cancer predicts cervical nodal metastasis, systemic relapse and survival
por: Pitkin, L, et al.
Publicado: (2007)

The presence of intraepithelial CD45RO+ cells in resected lymph nodes with metastases from NSCLC patients is an independent predictor of disease-specific survival
por: Kilvaer, Thomas K, et al.
Publicado: (2016)

Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4
por: Schimanski, C C, et al.
Publicado: (2006)

Nuclear survivin expression is associated with HPV-independent carcinogenesis and is an indicator of poor prognosis in oropharyngeal cancer
por: Preuss, S F, et al.
Publicado: (2008)

Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer
por: Boman, K, et al.
Publicado: (2013)

Hsp-27 expression at diagnosis predicts poor clinical outcome in prostate cancer independent of ETS-gene rearrangement
por: Foster, C S, et al.
Publicado: (2009)

Serum levels of chemokines CCL4 and CCL5 in cirrhotic patients indicate the presence of hepatocellular carcinoma
por: Sadeghi, M, et al.
Publicado: (2015)

CD133 expression is an independent prognostic marker for low survival in colorectal cancer
por: Horst, D, et al.
Publicado: (2008)

Soluble VE-cadherin in metastatic breast cancer: an independent prognostic factor for both progression-free survival and overall survival
por: Rochefort, Pauline, et al.
Publicado: (2017)

PROX1 is a predictor of survival for gliomas WHO grade II
por: Elsir, T, et al.
Publicado: (2011)

Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer
por: Frietsch, J J, et al.
Publicado: (2010)

ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survival
por: Brüning-Richardson, A, et al.
Publicado: (2011)

CTL- vs T(reg) lymphocyte-attracting chemokines, CCL4 and CCL20, are strong reciprocal predictive markers for survival of patients with oesophageal squamous cell carcinoma
por: Liu, J Y, et al.
Publicado: (2015)

Elevated mRNA expression of CHAC1 splicing variants is associated with poor outcome for breast and ovarian cancer patients
por: Goebel, G, et al.
Publicado: (2012)

Cell cycle times of short-term cultures of brain cancers as predictors of survival
por: Furneaux, C E, et al.
Publicado: (2008)

Polypeptide N-acetylgalactosaminyl transferase 3 independently predicts high-grade tumours and poor prognosis in patients with renal cell carcinomas
por: Kitada, S, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_biu4hu5o45o08ek5rkqqppa7nv