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How many strata in an RCT? A flexible approach

BACKGROUND: The need to allow for prognostic factors when designing and analysing cancer trials is well recognised, but the possibility of overstratification should be avoided by restricting the number of strata. The proposed method improves on existing guidance by being based on explicit principles...

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Detalles Bibliográficos
Autor principal: Silcocks, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314793/
https://www.ncbi.nlm.nih.gov/pubmed/22415237
http://dx.doi.org/10.1038/bjc.2012.84