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How many strata in an RCT? A flexible approach
BACKGROUND: The need to allow for prognostic factors when designing and analysing cancer trials is well recognised, but the possibility of overstratification should be avoided by restricting the number of strata. The proposed method improves on existing guidance by being based on explicit principles...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314793/ https://www.ncbi.nlm.nih.gov/pubmed/22415237 http://dx.doi.org/10.1038/bjc.2012.84 |