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Analysis of LIN28A in early human ovary development and as a candidate gene for primary ovarian insufficiency

Lin28 proteins are emerging as important regulators of microRNAs in endocrine systems. Lin28a regulates primordial germ cell development and puberty timing in mice, whereas the related protein LIN28B is associated with age at menarche in genome-wide association studies in humans. Here, we studied ex...

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Detalles Bibliográficos
Autores principales: El-Khairi, Ranna, Parnaik, Rahul, Duncan, Andrew J., Lin, Lin, Gerrelli, Dianne, Dattani, Mehul T., Conway, Gerard S., Achermann, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314903/
https://www.ncbi.nlm.nih.gov/pubmed/22240064
http://dx.doi.org/10.1016/j.mce.2011.12.016