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Micrococcal Nuclease Does Not Substantially Bias Nucleosome Mapping
We have mapped sequence-directed nucleosome positioning on genomic DNA molecules using high-throughput sequencing. Chromatins, prepared by reconstitution with either chicken or frog histones, were separately digested to mononucleosomes using either micrococcal nuclease (MNase) or caspase-activated D...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314939/ https://www.ncbi.nlm.nih.gov/pubmed/22310051 http://dx.doi.org/10.1016/j.jmb.2012.01.043 |