Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability

Sen1 of S. cerevisiae is a known component of the NRD complex implicated in transcription termination of nonpolyadenylated as well as some polyadenylated RNA polymerase II transcripts. We now show that Sen1 helicase possesses a wider function by restricting the occurrence of RNA:DNA hybrids that may...

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Detalles Bibliográficos
Autores principales: Mischo, Hannah E., Gómez-González, Belén, Grzechnik, Pawel, Rondón, Ana G., Wei, Wu, Steinmetz, Lars, Aguilera, Andrés, Proudfoot, Nick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314950/
https://www.ncbi.nlm.nih.gov/pubmed/21211720
http://dx.doi.org/10.1016/j.molcel.2010.12.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314950/
https://www.ncbi.nlm.nih.gov/pubmed/21211720
http://dx.doi.org/10.1016/j.molcel.2010.12.007

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