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Conformational Properties of the Unfolded State of Im7 in Nondenaturing Conditions

The unfolded ensemble in aqueous solution represents the starting point of protein folding. Characterisation of this species is often difficult since the native state is usually predominantly populated at equilibrium. Previous work has shown that the four-helix protein, Im7 (immunity protein 7), fol...

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Detalles Bibliográficos
Autores principales: Pashley, Clare L., Morgan, Gareth J., Kalverda, Arnout P., Thompson, Gary S., Kleanthous, Colin, Radford, Sheena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314952/
https://www.ncbi.nlm.nih.gov/pubmed/22226836
http://dx.doi.org/10.1016/j.jmb.2011.12.041