Salmonella Virulence Effector SopE and Host GEF ARNO Cooperate to Recruit and Activate WAVE to Trigger Bacterial Invasion

Salmonella virulence effectors elicit host cell membrane ruffling to facilitate pathogen invasion. The WAVE regulatory complex (WRC) governs the underlying membrane-localized actin polymerization, but how Salmonella manipulates WRC is unknown. We show that Rho GTPase activation by the Salmonella gua...

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Detalles Bibliográficos
Autores principales: Humphreys, Daniel, Davidson, Anthony, Hume, Peter J., Koronakis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314957/
https://www.ncbi.nlm.nih.gov/pubmed/22341462
http://dx.doi.org/10.1016/j.chom.2012.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314957/
https://www.ncbi.nlm.nih.gov/pubmed/22341462
http://dx.doi.org/10.1016/j.chom.2012.01.006

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