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A Bayesian View on Cryo-EM Structure Determination
Three-dimensional (3D) structure determination by single-particle analysis of cryo-electron microscopy (cryo-EM) images requires many parameters to be determined from extremely noisy data. This makes the method prone to overfitting, that is, when structures describe noise rather than signal, in part...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314964/ https://www.ncbi.nlm.nih.gov/pubmed/22100448 http://dx.doi.org/10.1016/j.jmb.2011.11.010 |