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Bioprocess design guided by in situ substrate supply and product removal: Process intensification for synthesis of (S)-1-(2-chlorophenyl)ethanol

We report herein on bioprocess development guided by the hydrophobicities of substrate and product. Bioreductions of o-chloroacetophenone are severely limited by instability of the catalyst in the presence of aromatic substrate and (S)-1-(2-chlorophenyl)ethanol. In situ substrate supply and product...

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Detalles Bibliográficos
Autores principales: Schmölzer, Katharina, Mädje, Katharina, Nidetzky, Bernd, Kratzer, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Applied Science, Elsevier Science Pub. Co 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314988/
https://www.ncbi.nlm.nih.gov/pubmed/22281147
http://dx.doi.org/10.1016/j.biortech.2012.01.009