Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers

Considerable evidence suggests that during the progression of complex diseases, the deteriorations are not necessarily smooth but are abrupt, and may cause a critical transition from one state to another at a tipping point. Here, we develop a model-free method to detect early-warning signals of such...

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Detalles Bibliográficos
Autores principales: Chen, Luonan, Liu, Rui, Liu, Zhi-Ping, Li, Meiyi, Aihara, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314989/
https://www.ncbi.nlm.nih.gov/pubmed/22461973
http://dx.doi.org/10.1038/srep00342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314989/
https://www.ncbi.nlm.nih.gov/pubmed/22461973
http://dx.doi.org/10.1038/srep00342

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