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Reactive oxygen species are involved in ferroportin degradation induced by ceruloplasmin mutant Arg701Trp

The ceruloplasmin mutant R701W, that causes a dramatic phenotype in the young heterozygous patient carrying this mutation, has been shown to have profound effects also in cell culture models. Here we show that Golgi rearrangement and degradation of the iron exporter ferroportin, that follow transfec...

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Detalles Bibliográficos
Autores principales: Persichini, Tiziana, De Francesco, Giovanni, Capone, Caterina, Cutone, Antimo, Bonaccorsi di Patti, Maria Carmela, Colasanti, Marco, Musci, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314996/
https://www.ncbi.nlm.nih.gov/pubmed/22281056
http://dx.doi.org/10.1016/j.neuint.2012.01.010