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Reactive oxygen species are involved in ferroportin degradation induced by ceruloplasmin mutant Arg701Trp
The ceruloplasmin mutant R701W, that causes a dramatic phenotype in the young heterozygous patient carrying this mutation, has been shown to have profound effects also in cell culture models. Here we show that Golgi rearrangement and degradation of the iron exporter ferroportin, that follow transfec...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314996/ https://www.ncbi.nlm.nih.gov/pubmed/22281056 http://dx.doi.org/10.1016/j.neuint.2012.01.010 |